Claudin-4 immunohistochemistry
WebAug 1, 2024 · Immunohistochemistry using claudin-4 and EZH2 was performed on cell block sections of these cases. Assessment of staining patterns, intensity and percentage … WebClaudin-4 immunohistochemistry is highly effective in distinguishing adenocarcinoma from malignant mesothelioma in effusion cytology. Cancer Cytopathol 2014;122:299-306. Chapel DB, Husain AN, Krausz T, et al. PAX8 Expression in a Subset of Malignant Peritoneal Mesotheliomas and Benign Mesothelium has Diagnostic Implications in the …
Claudin-4 immunohistochemistry
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WebWe present a study in which we assessed the expression of claudin 1 (CLDN1) and CLDN4 in oral squamous cell carcinoma (OSCC), as well as their prognostic relevance. Immunohistochemical analysis of CLDN1 and CLDN4 expression was carried out on tissue sections from 65 OSCCs. WebClaudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins . This gene encodes an integral membrane protein, which belongs to the claudin family.
WebClaudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The overexpression of Claudin-4 has been shown to decrease paracellular … WebClaudin-4 should be used as part of a panel of immunohistochemical stains to evaluate neoplasms of epithelial differentiation from benign mesothelial cells and mesothelial …
WebClaudin 11 Antibody (36-4500) in IHC (P) Immunohistochemistry analysis of Claudin-11 showing staining in the membrane of paraffin-embedded mouse brain tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8 … WebImmunogen Synthetic peptide within Human Claudin 1 aa 150 to the C-terminus (C terminal). The exact sequence is proprietary. Database link: O95832 General notes This product is FOR RESEARCH USE ONLY. For commercial use, please contact [email protected].
WebClaudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions. Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux.
WebAug 31, 2024 · claudin-4 Antibody (A-12) is an IgG 1 κ mouse monoclonal claudin-4 antibody (also designated Claudin 4 antibody or CLDN4 antibody) suitable for the detection of the claudin-4 protein of mouse, rat and human origin by WB, IP, IF, IHC (P) and ELISA. claudin-4 Antibody (A-12) is available as both the non-conjugated anti-claudin-4 … hoffman theater movie timesWebClaudin-4 is a component of tight junction strands and is expressed on the membrane of cells of epithelial origin. Claudin-4 has been shown to distinguish carcinoma from mesothelioma and carcinoma from sarcoma. Interpretation This test does not includes pathologist interpretation; only technical performance of the stain. h \u0026 r block langleyWebMar 24, 2024 · Other members of the claudin superfamily such as claudin-1, - 2, - 3 were described in detail in the lateral and fourth ventricle choroid plexus, playing a role in fluid and ion secretion. Interestingly, these proteins appear to also line the choroid and ependymal epithelia, as well as the circumventricular organs, probably contributing to ... h\u0026r block lakewood ranchWebResults: Claudin-6 expression was low for 61 of 123 (49.6%) NSCLC tissue samples and for 33 of 123 (26.8%) normal adjacent tissue samples. RT-PCR and western blot analyses confirmed the immunohistochemistry results. Claudin-6 expression was associated with lymph node metastasis ( P <0.001) and TNM stage ( P =0.007). h\u0026r block lancasterWebImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 4 antibody [EPRR17575] (ab210796) Immunohistochemical analysis of paraffin-embedded … h \u0026 r block lakeport caWebClaudin-4 should be used as part of a panel of immunohistochemical stains to evaluate neoplasms of epithelial differentiation from benign mesothelial cells and mesothelial neoplasms. Claudin-4 has a reported sensitivity ranging from 91-100% and a specificity of 94-100% for epithelial neoplasms. h\u0026r block las vegas near meWebNational Center for Biotechnology Information h\u0026r block lake in the hills il